might outperform
is always true. And if not today, then tomorrow or next month. Besides, most performance limitations are sitting behind the keyboard and drinking coffee or tea. A dbms does much more than just read data from a disk. If you don't need the extras, like transaction control, other software might (!) be a better match.
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Comment by Frank Heikens on Best Database for Bulk Reads and Fast Key Lookups for Genomic Data
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